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TIMD4 抗体 (AA 75-170)

The 兔 多克隆 anti-TIMD4 antibody is suitable to detect TIMD4 in samples from 人. It has been validated for ELISA, WB, IHC (p), IHC (fro), IF (p) 和 IF (cc).
产品编号 ABIN715631
发货至: 中国
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Quick Overview for TIMD4 抗体 (AA 75-170) (ABIN715631)

抗原

See all TIMD4 抗体
TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

适用

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宿主

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克隆类型

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多克隆

标记

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This TIMD4 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
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    AA 75-170

    预测反应

    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TIM4

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

    别名

    Tim4

    背景

    Synonyms: SMUCKLER, Spleen, mucin-containing, knockout of lymphotoxin protein, T cell immunoglobulin and mucin domain containing protein 4, T-cell immunoglobulin and mucin domain containing 4, T-cell membrane protein 4, TIM-4, Tim4, Tim 4, TIMD 4.

    Background: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. Studies have shown that TIM 4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM 1, and that this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM 4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM 4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM 1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

    基因ID

    91937

    途径

    Cancer Immune Checkpoints
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