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BID 抗体 (AA 100-150)

This anti-BID antibody is a 兔 多克隆 antibody detecting BID in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6990477
发货至: 中国

Quick Overview for BID 抗体 (AA 100-150) (ABIN6990477)

抗原

See all BID 抗体
BID (BH3 Interacting Domain Death Agonist (BID))

适用

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人, 小鼠

宿主

  • 156
  • 23
  • 1
  • 1

克隆类型

  • 148
  • 33
多克隆

标记

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This BID antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 25
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    AA 100-150

    纯化方法

    Bid Antibody is Ion exchange chromatography purified.

    免疫原

    Bid antibody was raised against a peptide corresponding to 14 amino acids near the middle of human Bid. The immunogen is located within amino acids 100 - 150 of Bid.

    亚型

    IgG
  • 应用备注

    Bid antibody can be used for detection of Bid by Western blot at 0.5 to 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Bid Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Bid antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BID (BH3 Interacting Domain Death Agonist (BID))

    别名

    Bid

    背景

    Bid Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize.

    基因ID

    637

    UniProt

    P55957

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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