TRIM5 抗体 (AA 390-440)
Our Local Distributor
北京 101111
Quick Overview for TRIM5 抗体 (AA 390-440) (ABIN6990449)
抗原
See all TRIM5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 390-440
-
特异性
- TRIM5 alpha antibody will not cross-react with other isoforms of TRIM5.
-
纯化方法
- TRIM5 alpha Antibody is affinity chromatography purified via peptide column.
-
免疫原
- TRIM5 alpha antibody was raised against a synthetic peptide corresponding to 19 amino acids near the center of rhesus monkey TRIM5 alpha. The immunogen is located within amino acids 390 - 440 of TRIM5 alpha.
-
亚型
- IgG
-
-
anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibody
Verified TRIM5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3B11H2 unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 1-493) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15830 unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (C-Term) antibodyTRIM5 适用: 人, 猴 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 100-200) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15815 unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 35-84) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
TRIM5 alpha antibody can be used for detection of TRIM5 alpha by Western blot at 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- TRIM5 alpha Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- TRIM5 alpha antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
-
别名
- TRIM5 alpha
-
背景
- TRIM5 alpha Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5α, variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. All TRIM5α, variants could inhibit at least two different retroviruses, but not from those viruses isolated from the same species, suggesting that TRIM5α, acts as a natural barrier to cross-species retrovirus transmission.
-
分子量
-
Predicted: 54 kDa
Observed: 54 kDa -
基因ID
- 574288
-
UniProt
- Q0PF16
-
途径
- Activation of Innate immune Response
抗原
-
