TRIM5 抗体 (C-Term)
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- 抗原 See all TRIM5 抗体
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- TRIM5 delta Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TRIM5 delta antibody was raised against a synthetic peptide corresponding to 13 amino acids near the carboxy terminus of human TRIM5 delta. The immunogen is located within the last 50 amino acids of TRIM5 delta.
- 亚型
- IgG
- Top Product
- Discover our top product TRIM5 Primary Antibody
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anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibody
Verified TRIM5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3B11H2 unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 1-493) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (C-Term) antibodyTRIM5 适用: 人, 猴 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 35-84) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 100-200) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (Middle Region 1) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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TRIM5 delta antibody can be used for detection of TRIM5 delta by Western blot at 2 μ,g/mL. A band at approximately 25 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 1 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TRIM5 delta Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TRIM5 delta antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- 别名
- TRIM5 delta (TRIM5 产品)
- 别名
- TRIM5 antibody, RNF88 antibody, TRIM5alpha antibody, EG667823 antibody, Gm8833 antibody, RGD1304579 antibody, tripartite motif containing 5 antibody, tripartite motif-containing 5 antibody, TRIM5 antibody, Trim5 antibody
- 背景
- TRIM5 delta Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5α, variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. The TRIM5δ, isoform has been shown to colocalize with the topoisomerase I-interacting proteins BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells where it appears to serve as a scaffold for the assembly of endogenous BTBD proteins. TRIM5δ, also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.
- 分子量
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Predicted: 36 kDa
Observed: 33 kDa - 基因ID
- 85363
- NCBI登录号
- NP_149084
- UniProt
- Q9C035
- 途径
- Activation of Innate immune Response
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