CARD10 抗体 (C-Term)
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北京 101111
Quick Overview for CARD10 抗体 (C-Term) (ABIN6990395)
抗原
See all CARD10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- CARD10 Antibody is immunoaffinity purified .
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免疫原
- CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10. The immunogen is located within the last 50 amino acids of CARD10.
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亚型
- IgG
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应用备注
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CARD10 antibody can be used for detection of CARD10 by Western blot at 5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CARD10 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CARD10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
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别名
- CARD10
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背景
- CARD10 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-κ,B. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the Iκ,K complex, demonstrating its importance in the regulation of NF-κ,B transcription factor activation.
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分子量
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Predicted: 116 kDa
Observed: 115 kDa -
基因ID
- 29775
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UniProt
- Q9BWT7
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途径
- S100 Proteins
抗原
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