CARD10 抗体 (AA 481-530)
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Quick Overview for CARD10 抗体 (AA 481-530) (ABIN1534304)
抗原
See all CARD10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 481-530
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原理
- CARD 10 Antibody
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特异性
- CARD 10 Polyclonal Antibody detects endogenous levels of CARD 10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CARD10. AA range:481-530
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
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别名
- CARD10
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背景
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Synonyms: CARD10, CARMA3, Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3, Carma 3
Background: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],
Gene Name: CARD10
Protein Name: Caspase recruitment domain-containing protein 10
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分子量
- 115 kDa
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基因ID
- 29775
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OMIM
- 607209
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UniProt
- Q9BWT7
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途径
- S100 Proteins
抗原
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