IRAK3 抗体 (C-Term)
Quick Overview for IRAK3 抗体 (C-Term) (ABIN6990358)
抗原
See all IRAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- IRAK-M antibody is predicted to have no cross reactivity to other members of the IRAK family.
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纯化方法
- IRAK-M Antibody is affinity chromatography purified via peptide column.
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免疫原
- IRAK-M antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRAK-M. The immunogen is located within the last 50 amino acids of IRAK-M.
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亚型
- IgG
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anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 454-596) antibody
IRAK3 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6G9G2 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 497-596) antibodyIRAK3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 1-596) antibodyIRAK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (Internal Region) antibodyVerified IRAK3 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) antibodyIRAK3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 1-596) antibodyIRAK3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 497-596) antibodyIRAK3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (C-Term) antibodyIRAK3 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 491-540) antibodyIRAK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (AA 367-596) antibodyIRAK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IRAK-M antibody can be used for detection of IRAK-M by Western blot at 1 μ,g/mL. IRAK-M antibody can also detect IRAK-M by immunohistochemistry at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in mouse and rat samples, Immunohistochemistry in human and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IRAK-M Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IRAK-M antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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别名
- IRAK-M
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背景
- IRAK-M Antibody: Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-betaB by IL-1/Toll receptors, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-betaB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS.
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分子量
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Predicted: 66 kDa
Observed: 70 kDa -
基因ID
- 11213
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NCBI登录号
- NP_009130
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UniProt
- Q9Y616
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途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
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