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BNIP3L/NIX 抗体 (AA 60-110)

This anti-BNIP3L/NIX antibody is a 兔 多克隆 antibody detecting BNIP3L/NIX in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6990342
发货至: 中国

Quick Overview for BNIP3L/NIX 抗体 (AA 60-110) (ABIN6990342)

抗原

See all BNIP3L/NIX (BNIP3L) 抗体
BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

适用

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宿主

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克隆类型

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多克隆

标记

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This BNIP3L/NIX antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 60-110

    特异性

    At least two isoforms of Bnip3L are known to exist.

    纯化方法

    Bnip3L Antibody is affinity chromatography purified via peptide column.

    免疫原

    Bnip3L antibody was raised against a 16 amino acid peptide near the center of human Bnip3L. The immunogen is located within amino acids 60 - 110 of Bnip3L.

    亚型

    IgG
  • 应用备注

    Bnip3L antibody can be used for detection of Bnip3L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Bnip3L Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Bnip3L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

    别名

    Bnip3L

    背景

    Bnip3L Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3alpha, and Nix (for Nip3-like protein X). Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues. Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.

    分子量

    Predicted: 24 kDa

    Observed: 36, 40 kDa

    基因ID

    665

    NCBI登录号

    NP_004322

    UniProt

    O60238

    途径

    Autophagy
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