IL1RAP 抗体 (C-Term)
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北京 101111
Quick Overview for IL1RAP 抗体 (C-Term) (ABIN6990297)
抗原
See all IL1RAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.
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纯化方法
- IL-1RAcP Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-1RAcP antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-1RAcP. The immunogen is located within the last 50 amino acids of IL-1RAcP.
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亚型
- IgG
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anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 65-249) antibody
IL1RAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 420-558) antibodyIL1RAP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 279-313) antibodyIL1RAP 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB57768 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 1-356) antibodyIL1RAP 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-356) antibodyIL1RAP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) antibodyIL1RAP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB13780 unconjugated Recombinant Antibody
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 484-518) antibodyIL1RAP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB57769 unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) antibodyIL1RAP 适用: 人, 小鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) antibodyIL1RAP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-367) antibodyIL1RAP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IL-1RAcP antibody can be used for detection of IL-1RAcP by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-1RAcP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-1RAcP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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别名
- IL-1RAcP
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背景
- IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κ,B inducing kinae (NIK) and of NF-κ,B, recruits to the IL-1R complex through IL-1RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
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分子量
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Predicted: 63 kDa
Observed: 66 kDa -
基因ID
- 3556
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NCBI登录号
- NP_001161401
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UniProt
- Q9NPH3
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途径
- NF-kappaB Signaling, Growth Factor Binding
抗原
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