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DAPK3 抗体 (AA 270-320)

This anti-DAPK3 antibody is a 兔 多克隆 antibody detecting DAPK3 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990278
发货至: 中国

Quick Overview for DAPK3 抗体 (AA 270-320) (ABIN6990278)

抗原

See all DAPK3 抗体
DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DAPK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 270-320

    纯化方法

    ZIPK Antibody is affinity chromatography purified via peptide column.

    免疫原

    ZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase. The immunogen is located within amino acids 270 - 320 of ZIPK.

    亚型

    IgG
  • 应用备注

    ZIPK antibody can be used for detection of DNase II expression by Western blot at 1 μ,g/mL. An approximate 40 kDa band can be detected, which represents the pro-enzyme of DNase II. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ZIPK Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ZIPK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))

    别名

    ZIPK

    背景

    ZIPK Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.

    分子量

    Predicted: 26 kDa

    Observed: 27 kDa

    基因ID

    1613

    UniProt

    O43293
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