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- 抗原 See all DAPK3 抗体
- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
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抗原表位
- Thr265
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAPK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human DAPK3 around the phosphorylation site of threonine 265 (R-M-T(p)-I-A).
- 亚型
- IgG
- Top Product
- Discover our top product DAPK3 Primary Antibody
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anti-Death-Associated Protein Kinase 3 (DAPK3) antibody
DAPK3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 1-100) antibodyDAPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 28-161) antibodyDAPK3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4H4C8 unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (N-Term) antibodyDAPK3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (Thr265) antibodyDAPK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 283-401) antibodyDAPK3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (pThr265) antibodyDAPK3 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 30-130) antibodyDAPK3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (pThr265) antibodyDAPK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 1-448) antibodyDAPK3 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
- 别名
- DAPK3 (DAPK3 产品)
- 别名
- DAPK3 antibody, dapk3 antibody, wu:fc25b08 antibody, si:dkey-57k2.5 antibody, MGC114871 antibody, ZIP antibody, ZIPK antibody, dlk antibody, Dapkl antibody, death associated protein kinase 3 antibody, death-associated protein kinase 3 antibody, death-associated protein kinase 3 L homeolog antibody, DAPK3 antibody, dapk3 antibody, dapk3.L antibody, Dapk3 antibody
- 背景
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Background: Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation, actin cytoskeleton reorganization, cell motility, smooth muscle contraction, and mitosis, particularly cytokinesis. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A, and the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca2+ and promote a contractile state. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Phosphorylates STAT3 and enhances its transcriptional activity. Positively regulates the canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2. Can disrupt the NLK-TCF7L2 complex thereby influencing the phosphorylation of TCF7L2 by NLK. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection. Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome, its association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition. Isoform 2 can phosphorylate myosin, PPP1R12A and MYL12B.
Kawai T., Mol. Cell. Biol. 18:1642-1651(1998).
Murata-Hori M., FEBS Lett. 451:81-84(1999).
The MGC Project Team, Genome Res. 14:2121-2127(2004).Aliases: DAP kinase 3 antibody, DAP like kinase antibody, DAP-like kinase antibody, Dapk 3 antibody, DAPK3 antibody, DAPK3_HUMAN antibody, Death associated kinase 3 antibody, Death associated protein kinase 3 antibody, Death-associated protein kinase 3 antibody, Dlk antibody, EC 2.7.11.1 antibody, FLJ36473 antibody, MYPT1 kinase antibody, ZIP antibody, ZIP kinase antibody, ZIP kinase isoform antibody, ZIP-kinase antibody, ZIPK antibody, zipper-interacting protein kinase antibody
- UniProt
- O43293
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