DAPK3 抗体 (AA 30-130)
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- 抗原 See all DAPK3 抗体
- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
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抗原表位
- AA 30-130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAPK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DAPK3
- 亚型
- IgG
- Top Product
- Discover our top product DAPK3 Primary Antibody
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anti-Death-Associated Protein Kinase 3 (DAPK3) antibody
DAPK3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 1-100) antibodyDAPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 28-161) antibodyDAPK3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4H4C8 unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (N-Term) antibodyDAPK3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (Thr265) antibodyDAPK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (Thr265) antibodyDAPK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 283-401) antibodyDAPK3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (pThr265) antibodyDAPK3 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (pThr265) antibodyDAPK3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Associated Protein Kinase 3 (DAPK3) (AA 1-448) antibodyDAPK3 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
- 别名
- DAPK3 (DAPK3 产品)
- 别名
- DAPK3 antibody, dapk3 antibody, wu:fc25b08 antibody, si:dkey-57k2.5 antibody, MGC114871 antibody, ZIP antibody, ZIPK antibody, dlk antibody, Dapkl antibody, death associated protein kinase 3 antibody, death-associated protein kinase 3 antibody, death-associated protein kinase 3 L homeolog antibody, DAPK3 antibody, dapk3 antibody, dapk3.L antibody, Dapk3 antibody
- 背景
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Synonyms: Death associated protein kinase 3, DAP kinase 3, DAP like kinase, Dapk 3, Dapk3, Death associated kinase 3, Death associated protein kinase 3, Dlk, FLJ36473, ZIP kinase, ZIPK, Zipper-interacting protein kinase, DAPK3_HUMAN.
Background: Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in regulation of starvation-induced autophagy. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A, the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca2+ and promote a contractile state. Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton. Isoform 2 can phosphorylate myosin, PPP1R12A and MYL12B. Overexpression leads to condensation of actin stress fibers into thick bundles. Involved in actin filament focal adhesion dynamics. The function in both reorganization of actin cytoskeleton and focal adhesion dissolution is modulated by RhoD. Positively regulates canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2. Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome, RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Involved in regulation of cell cycle progression and cell proliferation. May be a tumor suppressor.
- 基因ID
- 1613
- UniProt
- O43293
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