Caspase 10 抗体 (C-Term)
Quick Overview for Caspase 10 抗体 (C-Term) (ABIN6990247)
抗原
See all Caspase 10 (CASP10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-290, C-Term
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特异性
- Antibody only recognizes FLICE2 form of caspase-10.
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纯化方法
- Caspase-10 Antibody is Antibody is DEAE purified.
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免疫原
- Caspase-10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Caspase-10. The immunogen is located within amino acids 240 - 290 of Caspase-10.
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亚型
- IgG
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anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 223-459) antibody
CASP10 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibodyCASP10 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) antibodyCASP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) antibodyCASP10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 19-187) antibodyCASP10 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) antibodyCASP10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 220-521) antibodyCASP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 220-236), (N-Term) antibodyCASP10 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) antibodyCASP10 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 430-479) antibodyCASP10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Caspase-10 antibody can be used for detection of caspase-10 by Western blot 1 μ,g/mL. A 59 kDa band can be detected.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Caspase-10 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Caspase-10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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别名
- Caspase-10
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背景
- Caspase-10 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch4 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which causes the proteolytic cleavage of many key proteins such as PARP. Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death. Caspase-10 is expressed in many tissues and cell lines.
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基因ID
- 843
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UniProt
- Q92851
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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