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CCR3 抗体 (N-Term)

This anti-CCR3 antibody is a 兔 多克隆 antibody detecting CCR3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990238
发货至: 中国

Quick Overview for CCR3 抗体 (N-Term) (ABIN6990238)

抗原

See all CCR3 抗体
CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

适用

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人, 小鼠, 大鼠

宿主

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  • 5
  • 5

克隆类型

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  • 25
  • 1
多克隆

标记

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This CCR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    N-Term

    纯化方法

    CCR3 Antibody is immunoaffinity purified IgG.

    免疫原

    CCR3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human CCR3. The immunogen is located within the first 50 amino acids of CCR3.

    亚型

    IgG
  • 应用备注

    CCR3 antibody can be used for the detection of CCR3 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CCR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    CCR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))

    别名

    CCR3

    背景

    CCR3 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS. High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.

    基因ID

    1232

    NCBI登录号

    NP_847899

    UniProt

    P51677
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