CCR3 抗体 (C-Term)
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Quick Overview for CCR3 抗体 (C-Term) (ABIN6990236)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- At least three isoforms of CCR3 are known to exist, this antibody will detect all three isoforms.
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纯化方法
- CCR3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CCR3 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human CCR3. The immunogen is located within the last 50 amino acids of CCR3.
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亚型
- IgG
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anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody
CCR3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8E9H10 unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 251-355) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 306-355) antibodyCCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody (PE)CCR3 适用: 人 FACS 宿主: 小鼠 Monoclonal 5E8 PE
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (N-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (Extracellular Domain) antibodyCCR3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (N-Term) antibodyCCR3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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CCR3 antibody can be used for the detection of CCR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CCR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CCR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
- CCR3
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背景
- CCR3 Antibody: Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS. High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.
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分子量
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Predicted: 39, 41 kDa
Observed: 52 kDa -
基因ID
- 1232
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NCBI登录号
- NP_847899
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UniProt
- P51677
抗原
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