STAT5A 抗体 (pTyr694)
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- 抗原 See all STAT5A 抗体
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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抗原表位
- pTyr694
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This STAT5A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein
- 克隆位点
- 3H8
- 亚型
- IgG
- Top Product
- Discover our top product STAT5A Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
- 别名
- Stat5 (STAT5A 产品)
- 别名
- MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody
- 背景
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Synonyms: MGF antibody, Signal transducer and activator of transcription 5A antibody, Signal Transducer and Activator of Transcription 5B antibody, STA5A_HUMAN antibody, STAT 5A antibody, STAT 5B antibody, STAT5 antibody, STAT5A antibody, STAT5B antibody, Transcription factor STAT5A antibody, Transcription factor STAT5B antibody
Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- 基因ID
- 6776
- UniProt
- P42229
- 途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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