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PTBP1 抗体

This anti-PTBP1 antibody is a 兔 多克隆 antibody detecting PTBP1 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6989871
发货至: 中国

Quick Overview for PTBP1 抗体 (ABIN6989871)

抗原

See all PTBP1 抗体
PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

适用

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  • 3
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  • 2
  • 2
  • 1
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人, 小鼠, 大鼠

宿主

  • 49
  • 7
  • 1

克隆类型

  • 38
  • 19
多克隆

标记

  • 35
  • 3
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  • 2
  • 2
  • 2
  • 2
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  • 2
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  • 1
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This PTBP1 antibody is un-conjugated

应用范围

  • 39
  • 22
  • 19
  • 11
  • 7
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  • 6
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTBP1 (NP_114368.1).

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC()
    IF()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

    别名

    PTBP1

    背景

    Synonyms: PTBP1,HNRNP-I,HNRNPI,HNRPI,PTB,PTB-1,PTB-T,PTB2,PTB3,PTB4,pPTB

    Background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

    基因ID

    5725

    UniProt

    P26599

    途径

    Regulation of Muscle Cell Differentiation
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