Peroxiredoxin 3 抗体
Quick Overview for Peroxiredoxin 3 抗体 (ABIN6989866)
抗原
See all Peroxiredoxin 3 (PRDX3) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 63-256 of human PRDX3 (NP_006784.1).
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Peroxiredoxin 3 (PRDX3)
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别名
- PRDX3
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背景
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Synonyms: PRDX3,AOP-1,AOP1,HBC189,MER5,PRO1748,SP-22,prx-III
Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
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基因ID
- 10935
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UniProt
- P30048
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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