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Peroxiredoxin 3 抗体 (AA 110-256)

PRDX3 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043904
发货至: 中国
  • 抗原 See all Peroxiredoxin 3 (PRDX3) 抗体
    Peroxiredoxin 3 (PRDX3)
    抗原表位
    • 15
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    AA 110-256
    适用
    • 80
    • 41
    • 24
    • 2
    人, 大鼠, 小鼠
    宿主
    • 79
    • 8
    • 1
    • 1
    克隆类型
    • 75
    • 13
    多克隆
    标记
    • 45
    • 10
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Peroxiredoxin 3 antibody is un-conjugated
    应用范围
    • 65
    • 26
    • 19
    • 16
    • 15
    • 14
    • 14
    • 14
    • 10
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Thioredoxin-dependent peroxide reductase, mitochondrial(PRDX3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Thioredoxin-dependent peroxide reductase, mitochondrial(PRDX3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: peroxiredoxin 3
    Protein Name: Thioredoxin-dependent peroxide reductase, mitochondrial
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Peroxiredoxin 3 recombinant protein (Position: T110-Q256). Human Peroxiredoxin 3 shares 93% amino acid (aa) sequence identity with both mouse and rat Peroxiredoxin 3.
    亚型
    IgG
    Top Product
    Discover our top product PRDX3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Peroxiredoxin 3 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Peroxiredoxin 3 (PRDX3)
    别名
    PRDX3 (PRDX3 产品)
    别名
    cb718 antibody, wu:fk49e09 antibody, zgc:110282 antibody, zgc:112512 antibody, MGC83969 antibody, PRDX3 antibody, AOP-1 antibody, AOP1 antibody, HBC189 antibody, MER5 antibody, PRO1748 antibody, SP-22 antibody, prx-III antibody, AW822249 antibody, Aop1 antibody, D0Tohi1 antibody, Ef2l antibody, Mer5 antibody, Prx3 antibody, SP22 antibody, TDXM antibody, MTAP antibody, peroxiredoxin 3 antibody, peroxiredoxin 3 S homeolog antibody, peroxiredoxin PRX3 antibody, prdx3 antibody, PRDX3 antibody, prdx3.S antibody, PRX3 antibody, Prdx3 antibody
    背景
    PRDX3(peroxiredoxin 3) also known as AOP-1, MER5, SP-22 or PRX3, is localized exclusively in mitochondria. The deduced 256-amino acid human AOP1 protein shares 86 % amino acid sequence similarity with mouse Aop1, and significant similarity with both the human proliferation-associated gene A product and the mouse stress-induced peritoneal macrophage protein Msp23. The PRDX3 gene is mapped on 10q26.11. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that PRDX3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells. These data provided evidence that PRDX3 is a MYC target gene that is required to maintain normal mitochondrial function.

    Synonyms: Antioxidant Protein 1 antibody|AOP 1 antibody|AOP-1 antibody|AOP1 antibody|HBC189 antibody|MER 5 antibody|MER5 antibody|MGC104387 antibody|MGC24293 antibody|mitochondrial antibody|Mitochondrial thioredoxin dependent peroxide reductase antibody|peroxiredoxin 3 antibody|Peroxiredoxin III antibody|Peroxiredoxin-3 antibody|Peroxiredoxin3 antibody|PRDX 3 antibody|PRDX3 antibody|PRDX3_HUMAN antibody|PRO1748 antibody|Protein MER5 homolog antibody|PRX III antibody|Prx-III antibody|PRX3 antibody|SP 22 antibody|SP-22 antibody|SP22 antibody|Thioredoxin dependent peroxide reductase mitochondrial antibody|Thioredoxin dependent peroxide reductase precursor antibody|Thioredoxin-dependent peroxide reductase antibody
    基因ID
    10935
    UniProt
    P30048
    途径
    Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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