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CDK6 抗体

This anti-CDK6 antibody is a 兔 多克隆 antibody detecting CDK6 in WB, IHC, IF 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN6989758
发货至: 中国

Quick Overview for CDK6 抗体 (ABIN6989758)

抗原

See all CDK6 抗体
CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

适用

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  • 1
人, 小鼠

宿主

  • 103
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克隆类型

  • 89
  • 32
多克隆

标记

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This CDK6 antibody is un-conjugated

应用范围

  • 73
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human CDK6 (NP_001250.1).

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IP(1-2 μg)
    IHC()
    IF()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

    别名

    CDK6

    背景

    Synonyms: CDK6,MCPH12,PLSTIRE

    Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

    基因ID

    1021

    UniProt

    Q00534

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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