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Caspase 12 抗体 (AA 21-100)

This anti-Caspase 12 antibody (ABIN6989538) is a Rabbit Polyclonal antibody detecting Caspase 12 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro). Suitable for Mouse.
产品编号 ABIN6989538
发货至: 中国

Quick Overview for Caspase 12 抗体 (AA 21-100) (ABIN6989538)

抗原

See all Caspase 12 (CASP12) 抗体
Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

适用

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小鼠

宿主

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克隆类型

  • 90
  • 2
多克隆

标记

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This Caspase 12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 21-100

    交叉反应

    小鼠

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Caspase-12

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

    别名

    Caspase-12

    背景

    Synonyms: Caspase-12, UNQ9415, Apoptosis related cysteine protease, CASP 12, casp12, CASP12P1, Caspase 12 pseudogene 1, CASP-12, casp12, caspase 12 (gene/pseudogene), Caspase12, CASPC_HUMAN, OTTHUMP00000207026, OTTHUMP00000207028, OTTHUMP00000207031, OTTHUMP00000207032, OTTHUMP00000219058, UNQ9415.

    Background: Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011]

    基因ID

    100506742

    UniProt

    Q6UXS9

    途径

    Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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