电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MCL-1 抗体 (AA 101-200) (PE)

This anti-MCL-1 antibody is a 兔 多克隆 antibody detecting MCL-1 in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6988546
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MCL-1 抗体 (AA 101-200) (PE) (ABIN6988546)

抗原

See all MCL-1 (MCL1) 抗体
MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

适用

  • 154
  • 79
  • 75
  • 5
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 149
  • 11
  • 1
  • 1

克隆类型

  • 125
  • 39
多克隆

标记

  • 76
  • 11
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This MCL-1 antibody is conjugated to PE

应用范围

  • 131
  • 58
  • 55
  • 53
  • 43
  • 26
  • 26
  • 24
  • 21
  • 18
  • 7
  • 5
  • 4
Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 27
    • 16
    • 15
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MCL1

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

    别名

    MCL1

    背景

    Synonyms: myeloid cell leukemia 1, myeloid cell leukemia sequence 1, MCL-1, MCL1L, MCL 1, mcl1/EAT, MGC104264, MGC1839, TM, MCL1S, EAT) Bcl 2 related protein EAT/mcl1, BCL2 related, BCL2L3, EAT, Induced myeloid leukemia cell differentiation protein Mcl 1, myeloid cell leukemia sequence 1, Myeloid cell leukemia sequence 1 BCL2 related, Myeloid cell leukemia sequence 1 isoform 1, OTTHUMP00000032794, OTTHUMP00000032795, TM, bcl2-L-3, BCL2L3, EAT, Mcl-1, MCL1-ES, mcl1/EAT.

    Background: Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it. Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines ML1.

    基因ID

    4170

    UniProt

    Q07820

    途径

    MAPK Pathway
You are here: