电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Bcl-2 抗体 (AA 51-150) (HRP)

This anti-Bcl-2 antibody is a 小鼠 单克隆 antibody detecting Bcl-2 in WB. Suitable for 人, 小鼠, 大鼠, Pig, 绵羊, 兔, 犬, Cow, 豚鼠 和 马.
产品编号 ABIN6988060
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Bcl-2 抗体 (AA 51-150) (HRP) (ABIN6988060)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

  • 456
  • 180
  • 161
  • 35
  • 24
  • 23
  • 17
  • 7
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Pig, 绵羊, 兔, 犬, Cow, 豚鼠, 马

宿主

  • 359
  • 128
  • 4
  • 2
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 316
  • 180
单克隆

标记

  • 208
  • 34
  • 28
  • 20
  • 18
  • 12
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
This Bcl-2 antibody is conjugated to HRP

应用范围

  • 384
  • 201
  • 159
  • 143
  • 114
  • 95
  • 81
  • 72
  • 56
  • 55
  • 23
  • 22
  • 21
  • 17
  • 8
  • 8
  • 8
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

4D10
  • 抗原表位

    • 55
    • 38
    • 27
    • 24
    • 21
    • 21
    • 16
    • 16
    • 16
    • 12
    • 11
    • 11
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    交叉反应

    Cow, 犬, 豚鼠, 马, 人, 小鼠, Pig, 兔, 大鼠, 绵羊

    纯化方法

    Purified by Protein G.

    免疫原

    KLH conjugated synthetic peptide derived from human Bcl-2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    Bcl-2

    背景

    Synonyms: Apoptosis regulator Bcl 2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, Bcl 2, Bcl-2, Bcl2, BCL2 protein, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, BCL2_HUMAN.

    Background: The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14,18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8).

    基因ID

    596

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
You are here: