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GRK2 抗体 (pSer670) (Cy3)

ADRBK1 适用: 人, 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN6983415
发货至: 中国
  • 抗原 See all GRK2 (ADRBK1) 抗体
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    抗原表位
    • 15
    • 13
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer670
    适用
    • 91
    • 66
    • 46
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 83
    • 9
    • 3
    • 2
    克隆类型
    • 80
    • 17
    多克隆
    标记
    • 59
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRK2 antibody is conjugated to Cy3
    应用范围
    • 56
    • 44
    • 34
    • 17
    • 13
    • 12
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthesised phosphopeptide derived from human GRK2 around the phosphorylation site of Ser670
    亚型
    IgG
    Top Product
    Discover our top product ADRBK1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    别名
    GRK2 (ADRBK1 产品)
    背景

    Synonyms: GRK2 (phospho S670), p-GRK2 (phospho S670), G-protein coupled receptor kinase 2, ADRBK 1, ADRBK1, Adrenergic beta receptor kinase 1, BARK 1, BARK, BARK1, Beta adrenergic receptor kinase 1, Beta ARK 1, Beta ARK1, G Protein Coupled Receptor Kinase 2, G protein dependent receptor kinase 2, FLJ16718, GRK 2, ARBK1_HUMAN.

    Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].

    基因ID
    156
    UniProt
    P25098
    途径
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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