RAP1A 抗体 (AA 1-100) (Biotin)
Quick Overview for RAP1A 抗体 (AA 1-100) (Biotin) (ABIN6982932)
抗原
See all RAP1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RAP1A
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
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别名
- RAP1A
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背景
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Synonyms: C21KG, RAP1, G 22K, G-22K, GTP binding protein smg p21A, GTP-binding protein smg p21A, KREV 1, KREV-1, KREV1, OTTHUMP00000013741, RAP 1A, RAP1, RAP1A, RAP1A member of RAS oncogene family, RAP1A_HUMAN, Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, Ras-related protein Krev-1, Ras-related protein Rap-1A, SMGP21, rap1a, RAS-related protein-1a precursor, Rap1A-retro2, RAP1A, member of RAS oncogene family.
Background: Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.
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基因ID
- 5906
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UniProt
- P62834
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途径
- TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
抗原
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