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RAP1A 抗体 (Center)

RAP1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854404
发货至: 中国
  • 抗原 See all RAP1A 抗体
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    抗原表位
    • 15
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 47
    • 47
    • 17
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 56
    • 5
    克隆类型
    • 57
    • 4
    多克隆
    标记
    • 25
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAP1A antibody is un-conjugated
    应用范围
    • 48
    • 24
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠, 大鼠, 猕猴, 牛
    交叉反应 (详细)
    Mouse (100 %), Rat (100 %), Rhesus Monkey (100 %), Bovine (100 %)
    产品特性
    Rabbit polyclonal antibody to RAP1A (RAP1A, member of RAS oncogene family)
    RAP1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human RAP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product RAP1A Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.53 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chinigò, Grolez, Audero, Bokhobza, Bernardini, Cicero, Toillon, Bailleul, Visentin, Ruffinatti, Brysbaert, Lensink, De Ruyck, Cantelmo, Fiorio Pla, Gkika: "TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells." in: Cancers, Vol. 14, Issue 9, (2022) (PubMed).

  • 抗原
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    别名
    RAP1 (RAP1A 产品)
    别名
    KREV-1 antibody, KREV1 antibody, RAP1 antibody, SMGP21 antibody, AI848598 antibody, G-22K antibody, Krev-1 antibody, Rap1 antibody, RAP-1A antibody, rap 1A antibody, wu:fc66g06 antibody, zgc:86676 antibody, krev-1 antibody, krev1 antibody, rap1 antibody, RAP1A, member of RAS oncogene family antibody, RAS-related protein 1a antibody, RAP1A, member of RAS oncogene family a antibody, RAP1A, member of RAS oncogene family L homeolog antibody, RAP1A antibody, Rap1a antibody, rap1aa antibody, rap1a.L antibody
    背景
    The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

    Cellular Localization: Cell membrane, Lipid-anchor
    分子量
    21 kDa
    基因ID
    5906
    途径
    TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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