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LRP1 抗体 (AA 2501-2600) (Biotin)

This anti-LRP1 antibody is a 兔 多克隆 antibody detecting LRP1 in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN6982580
发货至: 中国

Quick Overview for LRP1 抗体 (AA 2501-2600) (Biotin) (ABIN6982580)

抗原

See all LRP1 抗体
LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LRP1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 2501-2600

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LRP1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

    别名

    LRP1

    背景

    Synonyms: A2MR, Alpha 2 macroglobulin receptor, alpha 2MR, APOER, Apolipoprotein E receptor, APR, CD 91, CD91, CD91 antigen, Low density lipoprotein receptor related protein 1, Low density lipoprotein related protein 1, LRP 1, LRP 515, LRP 85, LRP, LRP ICD, LRP1, LRP1 protein, LRP515.

    Background: Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, and may play a role in APP metabolism, kinase-dependent intracellular signalling, neuronal calcium signalling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

    基因ID

    4035

    UniProt

    Q07954

    途径

    Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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