PRAS40 抗体 (AA 161-256) (AbBy Fluor® 680)
Quick Overview for PRAS40 抗体 (AA 161-256) (AbBy Fluor® 680) (ABIN6980621)
抗原
See all PRAS40 (AKT1S1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-256
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交叉反应
- 人
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预测反应
- Mouse,Rat,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PRAS40
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亚型
- IgG
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anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibody
AKT1S1 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 6H1C6 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 152-276) antibodyAKT1S1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 92-276) antibodyAKT1S1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4A11G7 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 52-101) antibodyAKT1S1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr246) antibodyAKT1S1 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 132-256) antibodyAKT1S1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyAKT1S1 适用: 人 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 227-256) antibodyAKT1S1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) antibodyAKT1S1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1997CT730-74-73 unconjugated
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (pThr356) antibodyAKT1S1 适用: Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))
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别名
- PRAS40
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背景
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Synonyms: AKT1 substrate 1 (proline rich), AKT1 substrate 1, AKT1-S1, AKT1S-1, AKT1S 1, AKT1S1, Lobe, PRAS 40, PRAS-40, PRAS40, Proline rich akt substrate, 40 kDa proline rich AKT substrate, 40 kDa proline-rich AKT substrate, AKT1 S1, AKT1 substrate 1, AKTS1_HUMAN, MGC2865, PRAS40, Proline rich Akt substrate 40 kDa, Proline-rich AKT1 substrate 1.
Background: Proline Rich Akt Substrate (PRAS40) is a 40 kDa substrate of Akt. Akt and PRAS40 can be found in the phosphoinositide 3 kinase (PI3K) pathway, which plays a role in glucose uptake, cell growth, and apoptosis inhibition. PRAS40 is a 14-3-3 binding protein that reacts with insulin, but whose precise function is not yet known. It may bind SH3 and WW domain containing proteins resulting in a change of function. Activated Akt phosphorylates PRAS40 on threonine 246. Mutation of PRAS40 threonine 246 has been shown to be apoptotic.
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基因ID
- 84335
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UniProt
- Q96B36
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect
抗原
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