RAR-alpha (AA 428-441) 抗体
The 小鼠 单克隆 anti-RAR-alpha antibody is suitable to detect RAR-alpha in samples from 人. It has been validated for IHC, SSA 和 WB.
产品编号 ABIN6972585
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for RAR-alpha (AA 428-441) 抗体 (ABIN6972585)
抗原
RAR-alpha
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)
克隆位点
4gamma-7A11
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抗原表位
- AA 428-441
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产品特性
- Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-g has two splice isoforms. RAR-g heterodimerizes with RXR and in the absence of ligand, the RAR/RXR dimer binds to hormone response elements complexed with co-repressor protein. Binding of agonist ligands to RAR results in dissociation of co-repressor and recruitment of coactivator protein which in turn promotes transcription of the downstream target gene into mRNA and eventually protein. RAR-gamma antibody (mAb) (Clone 4g-7A11) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human samples.
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纯化方法
- Protein G Chromatography
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免疫原
- This RAR-γ antibody was raised against a recombinant protein corresponding to amino acids 428-441 (F-region) of human RARγ.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- RAR-alpha
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别名
- RAR-γ
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分子量
- 52 kDa
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NCBI登录号
- NP_000957
抗原
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