RAR-alpha (AA 420-443) 抗体
适用: 人, 小鼠
IHC, SSA, WB
宿主: 小鼠
Monoclonal
9alpha-9A6
unconjugated
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- 抗原
- RAR-alpha
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抗原表位
- AA 420-443
- 适用
- 人, 小鼠
-
宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
- 应用范围
- Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)
- 产品特性
- Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-a (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-a are sometimes involved in Promyelocytic leukemia. RAR-alpha antibody (mAb) (Clone 9a-9A6) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human and Mouse samples.
- 纯化方法
- Protein A Chromatography
- 免疫原
- This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.
- 克隆位点
- 9alpha-9A6
- 亚型
- IgG1 kappa
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in 60 mM Sodium Citrate, 105 mM Tris-HCl, 30 % glycerol, and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- RAR-alpha
- 别名
- RAR-α
- 分子量
- 52 kDa
- NCBI登录号
- NP_001138773
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