PRMT6 抗体 (N-Term)
Quick Overview for PRMT6 抗体 (N-Term) (ABIN6972556)
抗原
See all PRMT6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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产品特性
- PRMT6 (Protein Arginine Methyltransferase 6, HRMT1L6, ANM6) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT6 preferentially methylates arginine residues present in GAR (glycine and arginine-rich) domains. PRMT6 asymmetrically dimethylates histone H3 at Arg2, which is mutually exclusive to methylation at lysine 4 (associated with transcriptional activation), and thus PRMT6 serves as a transcriptional repressor in this context. It can also symmetrically dimethylate H2A and H4 at Arg3 and serves as a coactivator of transcription in concert with nuclear receptors. PRMT6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunohistochemistry and Western blot, it has been shown to react with Human samples.
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纯化方法
- Affinity Purified
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免疫原
- This PRMT6 antibody was raised against a peptide corresponding to amino acids within the N-terminal region of PRMT6.
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亚型
- IgG
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anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibody
PRMT6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 19-48) antibodyPRMT6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 119-375) antibodyPRMT6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibodyPRMT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibodyPRMT6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) antibodyPRMT6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 301-375) antibodyPRMT6 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (C-Term) antibodyPRMT6 适用: 人, 大鼠, 犬, 马, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 275-324) antibodyPRMT6 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (Internal Region) antibodyVerified PRMT6 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
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别名
- PRMT6
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分子量
- 42 kDa
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NCBI登录号
- NP_060607
抗原
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