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IL12 抗体

Cited in 5+ publications. The 大鼠 单克隆 anti-IL12 antibody (Clone C17-8) (ABIN6963865) specifically detects IL12 in ELISA 和 ELISpot. The antibody is reactive with 小鼠 samples.
产品编号 ABIN6963865
发货至: 中国
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Quick Overview for IL12 抗体 (ABIN6963865)

抗原

See all IL12 抗体
IL12 (Interleukin 12 (IL12))

适用

  • 48
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小鼠

宿主

  • 34
  • 27
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  • 2
  • 1
大鼠

克隆类型

  • 50
  • 37
单克隆

标记

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This IL12 antibody is un-conjugated

应用范围

  • 69
  • 55
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ELISA, ELISpot

克隆位点

C17-8
  • 特异性

    Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

    纯化方法

    Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant mouse IL-12 p70

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    supplied at 1 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Ashrafi, Shapouri, Shirkhani, Mahdavi: "Anti-tumor effects of propranolol: Adjuvant activity on a transplanted murine breast cancer model." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 45-51, (2018) (PubMed).

    Yazdi, Varastehmoradi, Faghfuri, Mavandadnejad, Mahdavi, Shahverdi: "Adjuvant Effect of Biogenic Selenium Nanoparticles Improves the Immune Responses and Survival of Mice Receiving 4T1 Cell Antigens as Vaccine in Breast Cancer Murine Model." in: Journal of nanoscience and nanotechnology, Vol. 15, Issue 12, pp. 10165-72, (2017) (PubMed).

    Almeida, Breyner, Mahi, Ahmed, Benbouziane, Boas, Miyoshi, Azevedo, Langella, Bermúdez-Humarán, Chatel: "Expression of fibronectin binding protein A (FnBPA) from Staphylococcus aureus at the cell surface of Lactococcus lactis improves its immunomodulatory properties when used as protein delivery vector." in: Vaccine, Vol. 34, Issue 10, pp. 1312-8, (2016) (PubMed).

    Tadepalli, Singh, Balakrishna, Murali, Batra: "Immunogenicity and protective efficacy of Brucella abortus recombinant protein cocktail (rOmp19+rP39) against B. abortus 544 and B. melitensis 16M infection in murine model." in: Molecular immunology, Vol. 71, pp. 34-41, (2016) (PubMed).

    Zhang, Wang, Liu, Chen, Li, Yang, An, Ma, Pan, Ma: "Comparison of PLA microparticles and alum as adjuvants for H5N1 influenza split vaccine: adjuvanticity evaluation and preliminary action mode analysis." in: Pharmaceutical research, Vol. 31, Issue 4, pp. 1015-31, (2014) (PubMed).

  • 抗原

    IL12 (Interleukin 12 (IL12))

    别名

    IL12 (p70)

    基因ID

    16159, 16160

    途径

    JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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