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IL12 抗体 (Biotin)

There are 5+ publications for this product available. The 小鼠 单克隆 anti-IL12 antibody is suitable to detect IL12 in samples from 人 和 Non-Human Primate. It has been validated for ELISA 和 ELISpot.
产品编号 ABIN6963864
发货至: 中国
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Quick Overview for IL12 抗体 (Biotin) (ABIN6963864)

抗原

See all IL12 抗体
IL12 (Interleukin 12 (IL12))

适用

  • 47
  • 19
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  • 1
人, Non-Human Primate

宿主

  • 34
  • 26
  • 14
  • 12
  • 2
  • 1
小鼠

克隆类型

  • 50
  • 37
单克隆

标记

  • 39
  • 12
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  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 1
This IL12 antibody is conjugated to Biotin

应用范围

  • 69
  • 55
  • 26
  • 26
  • 14
  • 10
  • 9
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  • 6
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  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, ELISpot

克隆位点

MT704
  • 特异性

    IL-12 (p70)

    交叉反应 (详细)

    The monoclonal antibody cross-reacts with IL-12 (p70) from non-human primates.

    产品特性

    This monoclonal antibody enables specific detection of human IL-12 (p70) in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

    纯化方法

    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IL-12 p70

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    ABIN6963864 and ABIN7448307 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

    有效期

    18 months
  • Tomasicchio, Semple, Esmail, Meldau, Randall, Pooran, Davids, Cairncross, Anderson, Downs, Malherbe, Novitzky, Panieri, Oelofse, Londt, Naiker, Dheda: "An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells." in: Cancer immunology, immunotherapy : CII, Vol. 68, Issue 1, pp. 71-83, (2019) (PubMed).

    Tootoonchian, Pak, Ardekani, Sehati, Abedi-Valugerdi, Kokhaei: "Evaluation of interleukin 12 and CD56+ lymphocyte cells in pediatric hematopoietic stem cell transplantation for early diagnosis of acute graft versus host disease." in: Transplant immunology, Vol. 39, pp. 25-29, (2018) (PubMed).

    Tagawa, Albanese, Bouvet, Moosmann, Mautner, Heissmeyer, Zielinski, Lutter, Hoser, Hastreiter, Hayes, Sugden, Hammerschmidt: "Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing." in: The Journal of experimental medicine, Vol. 213, Issue 10, pp. 2065-80, (2017) (PubMed).

    Zhang, Morgan, Beane, Zheng, Dudley, Kassim, Nahvi, Ngo, Sherry, Phan, Hughes, Kammula, Feldman, Toomey, Kerkar, Restifo, Yang, Rosenberg: "Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 10, pp. 2278-88, (2016) (PubMed).

    Persson, Ekerfelt, Jablonowska, Jonsson, Ernerudh, Jenmalm, Berg: "Immunological status in patients undergoing in vitro fertilisation: responses to hormone treatment and relationship to outcome." in: Journal of reproductive immunology, Vol. 96, Issue 1-2, pp. 58-67, (2013) (PubMed).

  • 抗原

    IL12 (Interleukin 12 (IL12))

    别名

    IL12 (p70)

    基因ID

    3592, 3593

    途径

    JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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