IL12 抗体 (Biotin)
Quick Overview for IL12 抗体 (Biotin) (ABIN6963864)
抗原
See all IL12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- IL-12 (p70)
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交叉反应 (详细)
- The monoclonal antibody cross-reacts with IL-12 (p70) from non-human primates.
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产品特性
- This monoclonal antibody enables specific detection of human IL-12 (p70) in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples
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纯化方法
- Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human IL-12 p70
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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ABIN6963864 and ABIN7448307 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs .
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
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有效期
- 18 months
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: "An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells." in: Cancer immunology, immunotherapy : CII, Vol. 68, Issue 1, pp. 71-83, (2019) (PubMed).
: "Evaluation of interleukin 12 and CD56+ lymphocyte cells in pediatric hematopoietic stem cell transplantation for early diagnosis of acute graft versus host disease." in: Transplant immunology, Vol. 39, pp. 25-29, (2018) (PubMed).
: "Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing." in: The Journal of experimental medicine, Vol. 213, Issue 10, pp. 2065-80, (2017) (PubMed).
: "Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 10, pp. 2278-88, (2016) (PubMed).
: "Immunological status in patients undergoing in vitro fertilisation: responses to hormone treatment and relationship to outcome." in: Journal of reproductive immunology, Vol. 96, Issue 1-2, pp. 58-67, (2013) (PubMed).
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: "An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells." in: Cancer immunology, immunotherapy : CII, Vol. 68, Issue 1, pp. 71-83, (2019) (PubMed).
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- IL12 (Interleukin 12 (IL12))
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别名
- IL12 (p70)
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基因ID
- 3592, 3593
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途径
- JAK/STAT Signaling, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
抗原
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