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CD44 抗体

This anti-CD44 antibody is a 大鼠 单克隆 antibody detecting CD44 in FACS, WB, IHC (p), IP 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN6961738
发货至: 中国

Quick Overview for CD44 抗体 (ABIN6961738)

抗原

See all CD44 抗体
CD44

适用

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人, 小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

IM7
  • 交叉反应

    Baboon, Cat, Chimpanzee, Cynomolgus, 犬, 马, Pig, 猕猴

    纯化方法

    This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

    亚型

    IgG2b kappa
  • 应用备注

    This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.

    说明

    0.5 mg/mL

    限制

    仅限研究用
  • 缓冲液

    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C

    有效期

    12 months
  • 抗原

    CD44

    别名

    CD44

    背景

    The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organiza- tion, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or ""standard"" form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion. The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

    基因ID

    12505, 960

    UniProt

    P16070, P15379

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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