FASL 抗体
Quick Overview for FASL 抗体 (ABIN6961471)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
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内毒素水平
- Low endotoxin: < 0.01 EU/ug
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亚型
- IgG1 kappa
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应用备注
- This antibody preparation has been quality-tested for flow cytometry using an appropriate cell type. The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. Tonbo Biosciences tests all of our antibodies by flow cytometry. Citations may be provided as a resource for additional applications that have not been validated by Tonbo Biosciences.
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说明
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2.0 mg/mL
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限制
- 仅限研究用
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缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- 2-8°C
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有效期
- 12 months
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- CD178 (Fas ligand)
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背景
- The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
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基因ID
- 356
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UniProt
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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