CSF1R 抗体
Quick Overview for CSF1R 抗体 (ABIN6961453)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
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内毒素水平
- Low endotoxin: < 0.01 EU/ug
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亚型
- IgG2a kappa
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anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody
CSF1R 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 6B9B9 unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibodyCSF1R 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6B9H2 unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (pTyr723) antibodyCSF1R 适用: 人, 犬 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 940-971) antibodyCSF1R 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (Tyr809) antibodyCSF1R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 21-120) antibodyCSF1R 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3G12 unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 20-152) antibodyCSF1R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4C9G2 unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 895-923), (C-Term) antibodyCSF1R 适用: 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB34462 unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 895-923) antibodyCSF1R 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 201-300) antibodyCSF1R 适用: 人 ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
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说明
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2 mg/mL
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限制
- 仅限研究用
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缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- 2-8°C
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有效期
- 12 months
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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别名
- CD115 (c-fms)
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背景
- The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid pre- cursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteo- clasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.The AFS98 antibody may be used for identification of myeloid lineage cells by flow cytometry, and is commonly used for in vivo or in vitro neutralization of CSF-1 Receptor.
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基因ID
- 12978
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UniProt
- P09581
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途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
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