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EZH2 抗体 (AA 1-343)

This anti-EZH2 antibody is a 兔 多克隆 antibody detecting EZH2 in WB, IF, ChIP 和 ChIP-seq. Suitable for 人.
产品编号 ABIN6952425
发货至: 中国

Quick Overview for EZH2 抗体 (AA 1-343) (ABIN6952425)

抗原

See all EZH2 抗体
EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

适用

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宿主

  • 90
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克隆类型

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多克隆

标记

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This EZH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

质量等级

ChIP-seq Grade
  • 抗原表位

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    AA 1-343

    特异性

    Polyclonal antibody raised in rabbit against the N-terminus (aa1-343) of the mouse EZH2 protein (Enhancer of zeste homolog 2).

    交叉反应

    小鼠

    纯化方法

    Protein G purified

    免疫原

    recombinant protein
  • 应用备注

    ChIP/ChIP-seq 2 μg:ChIP
    WB 1:1,000
    IF 1:1,000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    PBS, 0.05 % azide, 0.05 % ProClin300

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

    别名

    EZH2

    背景

    EZH2 (UniProt/Swiss-Prot entry Q15910) is a histone-lysine methyltransferase which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression. It is a member of the polycomb group (PcG) family which form multimeric protein complexes and are involved in maintaining the transcriptional repressive state of genes over successive cell generations. The EZH2 activity is dependent on the association with other components of the PRC2 complex (EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7). EZH2 may play a role in the hematopoietic and central nervous systems. Over-expression of EZH2 is observed during advanced stages of prostate cancer and breast cancer.

    UniProt

    Q15910

    途径

    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
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