p300 抗体
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北京 101111
Quick Overview for p300 抗体 (ABIN6952378)
抗原
See all p300 (EP300) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- Monoclonal antibody raised in mouse against human p300 (E1A Binding Protein P300) by DNA immunization in which the C-terminal part of the protein was cloned and expressed.
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纯化方法
- Protein A purified
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免疫原
- DNA immunization
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亚型
- IgG3
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anti-E1A Binding Protein P300 (EP300) (AA 731-830) antibody
EP300 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-E1A Binding Protein P300 (EP300) (AA 2065-2414) antibodyEP300 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) (AA 1351-1601) antibodyEP300 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) (N-Term) antibodyEP300 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) (AA 2283-2414) antibodyEP300 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) (AA 1-158) antibodyEP300 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) antibodyEP300 适用: 人 WB, IP, IF, ICC, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal NM11 unconjugated
anti-E1A Binding Protein P300 (EP300) (AA 2124-2397) antibodyEP300 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) antibodyEP300 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E1A Binding Protein P300 (EP300) (N-Term) antibodyEP300 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ChIP/ChIP-seq 5 μg:ChIP
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.9 μg/μL
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缓冲液
- PBS, 0.05 % azide, 0.05 % ProClin300
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- p300 (EP300) (E1A Binding Protein P300 (EP300))
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别名
- p300
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背景
- P300 (UniProt/Swiss-Prot entry Q09472) is a histone acetyltransferase that regulates transcription via chromatin remodelling. As such it is important for cell proliferation and differentiation. p300 is able to acetylate all four core histones in nucleosomes. Acetylation of histones is associated with transcriptional activation. p300 also acetylates non-histone proteins such as HDAC1 leading to its inactivation and modulation of transcription. It has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in the p300 gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
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UniProt
- Q09472
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途径
- p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
抗原
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