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Growth Hormone 1 抗体

The 小鼠 单克隆 anti-Growth Hormone 1 antibody is suitable to detect Growth Hormone 1 in samples from 人. It has been validated for IHC.
产品编号 ABIN6950857
发货至: 中国
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Quick Overview for Growth Hormone 1 抗体 (ABIN6950857)

抗原

See all Growth Hormone 1 (GH1) 抗体
Growth Hormone 1 (GH1)

适用

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人

宿主

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小鼠

克隆类型

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单克隆

标记

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This Growth Hormone 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 原理

    GH/ hPL mouse mAb

    特异性

    The antibody can recognize human Placental lactogen, and has cross-reactiin with GH protein.

    纯化方法

    The antibody was purified by affinity chromatography using a specific immunogen.

    免疫原

    A synthetic peptide corresponding to the amino acid region 150 - 217 of the human GH/ hPL protein.

    亚型

    IgG
  • 应用备注

    IHC, 1:200-1:400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    Growth Hormone 1 (GH1)

    别名

    Growth Hormone (GH)

    背景

    Synonyms: Lactogen, Placental lactogen, PL, hPL, gH, GH-N, GH1, GHB5, GHN, Growth hormone 1, Growth hormone, Growth hormone B5, Growth hormone, normal, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, SOMA_HUMAN, Somatotropin

    Background: Human placental prolactin (HPL) is a 22 kD polypeptide hormone synthesized and secreted by placental syncytiotrophoblast cells, has partial homology with growth hormone. It is expressed in normal placenta, choriocarcinoma, testicular cancer. Anti-HPL antibody is commonly used in the study of trophoblastic tumors. Growth hormone (GH) is a hormone synthesized and secreted by growth hormone cells in the anterior pituitary, which can promote protein synthesis and bone development. The mechanism of stimulating body growth is to stimulate the secretion of IGF-1 by liver and other tissues. It is mainly used for the functional classification of pituitary tumor and the differentiation of primary pituitary tumor and metastatic cancer.

    Gene Name: CSH1 CSH2 GH1

    Protein Name: GH/ hPL

    UniProt

    P01241

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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