TFAM 抗体 (AA 50-150)
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北京 101111
Quick Overview for TFAM 抗体 (AA 50-150) (ABIN6945143)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-150
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原理
- TFAM (16A1) Monoclonal Antibody
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide within human mtTFA aa 50-150
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:20-100), IF(IHC-P)(1:200-400), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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别名
- TFAM
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背景
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Synonyms: Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2, mtTFA, MtTF1, TCF-6, TFAM, TCF6, TCF6L2.
Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
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基因ID
- 7019
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UniProt
- Q00059
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途径
- Chromatin Binding
抗原
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