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SUMO1 抗体 (AA 1-100)

This 兔 单克隆 antibody specifically detects SUMO1 in WB, IHC, FACS, IHC (p) 和 IF (cc). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN6945096
发货至: 中国
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Quick Overview for SUMO1 抗体 (AA 1-100) (ABIN6945096)

抗原

See all SUMO1 抗体
SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

适用

  • 171
  • 92
  • 84
  • 6
  • 5
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  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
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  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 141
  • 37
  • 3
  • 1
  • 1

克隆类型

  • 116
  • 68
单克隆

标记

  • 78
  • 14
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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SUMO1 antibody is un-conjugated

应用范围

  • 138
  • 65
  • 61
  • 61
  • 46
  • 28
  • 26
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  • 20
  • 7
  • 6
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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

7H5
  • 抗原表位

    • 21
    • 15
    • 15
    • 12
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100

    原理

    SUMO-1 (7H5) Monoclonal Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human Sumo 1 aa 1-100

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), FCM(1:200-400), IHC-P(1:100-500), IF(ICC)(1:50-200), IHC(1 μg/Test)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

    别名

    SUMO-1

    背景

    Synonyms: Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, SUMO-1, GMP1, Smt3C, SUMO1, SMT3C, SMT3H3, UBL1

    Background: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.

    基因ID

    7341

    UniProt

    P63165

    途径

    M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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