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Sonic Hedgehog 抗体 (AA 250-350)

The 兔 单克隆 anti-Sonic Hedgehog antibody (Clone 4C10) (ABIN6944987) specifically detects Sonic Hedgehog in WB, IHC, FACS, IHC (p) 和 IF (cc). The antibody is reactive with 人 samples.
产品编号 ABIN6944987
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Sonic Hedgehog 抗体 (AA 250-350) (ABIN6944987)

抗原

See all Sonic Hedgehog (SHH) 抗体
Sonic Hedgehog (SHH)

适用

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宿主

  • 104
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克隆类型

  • 84
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单克隆

标记

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This Sonic Hedgehog antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

4C10
  • 抗原表位

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    AA 250-350

    原理

    Sonic Hedgehog Protein (C-Product) (4C10) Monoclonal Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Human Sonic Hedgehog between 250-350 amino acids

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), FCM(1:200-400), IHC-P(1:100-500), IF(ICC)(1:50-200), IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Sonic Hedgehog (SHH)

    别名

    Sonic Hedgehog Protein (C-Product)

    背景

    Synonyms: Sonic hedgehog protein, HHG-1, SHH

    Background: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).

    基因ID

    6469

    UniProt

    Q15465

    途径

    Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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