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SIRT1 抗体 (AA 700-800)

The 兔 单克隆 anti-SIRT1 antibody is suitable to detect SIRT1 in samples from 人 和 小鼠. It has been validated for WB, IHC 和 IF (cc).
产品编号 ABIN6944884
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SIRT1 抗体 (AA 700-800) (ABIN6944884)

抗原

See all SIRT1 抗体
SIRT1 (Sirtuin 1 (SIRT1))

适用

  • 216
  • 40
  • 26
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 197
  • 27
  • 2
  • 2

克隆类型

  • 148
  • 80
单克隆

标记

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  • 7
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  • 2
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  • 1
This SIRT1 antibody is un-conjugated

应用范围

  • 180
  • 82
  • 71
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  • 47
  • 42
  • 42
  • 33
  • 16
  • 10
  • 4
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

3C7
  • 抗原表位

    • 46
    • 16
    • 16
    • 13
    • 12
    • 12
    • 8
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    • 6
    • 5
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-800

    原理

    SIRT1 (3C7) Monoclonal Antibody

    交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human SIRT1 between 700-800 amino acids

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IF(ICC)(1:50-200), IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SIRT1 (Sirtuin 1 (SIRT1))

    别名

    SIRT1

    背景

    Synonyms: NAD-dependent protein deacetylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIRT1, hSIR2, SIRT1

    Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

    基因ID

    23411

    UniProt

    Q96EB6

    途径

    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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