SF3B3 抗体
Quick Overview for SF3B3 抗体 (ABIN6944865)
抗原
See all SF3B3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
- 
    - 
                                            交叉反应
- 人, 小鼠, 大鼠
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- Recombinant protein within the C-terminus of human SF3B3.
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- 
                        WB 1:300-5000
 FCM 1:20-100
 IHC-P 1:200-400
 IF(IHC-P) 1:50-200
 IF(ICC) 1:50-200
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 
                                            储存液
- ProClin
- 
                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            储存条件
- 4 °C,-20 °C
- 
                                            储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 
                                            有效期
- 12 months
 
- 
                                            
- 
    - SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- 
                                            别名
- SF3B3
- 
                                            背景
- 
                        Synonyms: Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130 kDa subunit, STAF130, Spliceosome-associated protein 130, SF3b130, SF3B3, SAP130 Background: SF3B is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130 (also known as SF3B3), SAP 145 and SAP 155. SF3B3, SAP 145 and SAP 155 are present in a protein complex in HeLa nuclear extracts and associate with one another. While SF3B3 and SAP 155 interact with each other (directly or indirectly) within this complex, SAP 49 and SAP 145 are known to interact directly with each other. Unexpectedly, the SAP 49-SAP 145 protein-protein interaction requires the amino-terminus of SAP 49, which contains two RNA-recognition motifs. The observation that SAP 49 and SAP 145 interact directly with both U2 snRNP and the pre-mRNA suggests that this protein complex plays a role in tethering U2 snRNP to the branch site. 
- 
                                            基因ID
- 23450
- 
                                            UniProt
- Q15393
 抗原
- 
                    
 
                                     
                                     
                                    