PTBP1 抗体
Quick Overview for PTBP1 抗体 (ABIN6944694)
抗原
See all PTBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant protein within human PTBP1 1-200
-
亚型
- IgG
-
-
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-144) antibody
PTBP1 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibodyVerified PTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-100) antibodyPTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-290) antibodyPTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibodyPTBP1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibodyPTBP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 8A1 unconjugated Recombinant Antibody
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibodyPTBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 26-55), (N-Term) antibodyPTBP1 适用: 人 WB 宿主: 兔 Polyclonal RB40967 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-557) antibodyPTBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-145) antibodyPTBP1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3H8 unconjugated
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 12 months
-
-
- PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
-
别名
- PTBP1
-
背景
-
Synonyms: Polypyrimidine tract-binding protein 1, 57 kDa RNA-binding protein PPTB-1, Heterogeneous nuclear ribonucleoprotein I, PTB, hnRNP I, PTBP1.
Background: PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). PTBP1 a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.
-
基因ID
- 5725
-
UniProt
- P26599
-
途径
- Regulation of Muscle Cell Differentiation
抗原
-
