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PEN2 抗体

This anti-PEN2 antibody is a 兔 单克隆 antibody detecting PEN2 in WB, IF (cc), IF (p), IHC (p) 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6944688
发货至: 中国

Quick Overview for PEN2 抗体 (ABIN6944688)

抗原

See all PEN2 (PSENEN) 抗体
PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This PEN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

1D8
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide corresponding to C-terminal human PEN2.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

    别名

    PSENEN

    背景

    Synonyms: Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN, PEN2, presenilin enhancer gamma-secretase subunit, MDS033

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

    基因ID

    55851

    UniProt

    Q9NZ42

    途径

    Notch Signaling, Neurotrophin Signaling Pathway
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