PRMT5 抗体
Quick Overview for PRMT5 抗体 (ABIN6944659)
抗原
See all PRMT5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Human PRMT5 between 50-150 amino acids
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亚型
- IgG
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anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 40-140) antibody
PRMT5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (Internal Region) antibodyPRMT5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 21-70) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 猴, 豚鼠, Pig, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 297-534) antibodyPRMT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 2H4 unconjugated Recombinant Antibody
anti-Protein Arginine Methyltransferase 5 (PRMT5) antibodyPRMT5 适用: 人, 小鼠 WB, IHC, IF, IP, ChIP, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (N-Term) antibodyPRMT5 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 591-621) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 5 (PRMT5) (AA 76-104) antibodyPRMT5 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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别名
- PRMT5
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背景
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Synonyms: Protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog, SKB1 homolog, SKB1Hs, HRMT1L5, IBP72, JBP1, SKB1
Background: DescriptionThe formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs. This process is mediated by the survival of a motor neuron (SMN) protein and is enhanced by modification of specific Arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs). sDMA modification of Sm proteins is catalyzed by the methylosome, a complex comprised of the type II methyltransferase PRMT5, also designated JAK-binding protein 1), (JBP1), pICln, and two novel factors. PRMT5 binds the Sm proteins via their Arginine- and Glycine-rich (RG) domains, while pICln binds the Sm domains. PRMT5 is a distinct member of the protein-Arginine methyltransferase (PRMT) family, and predominantly localizes to the cytoplasm in a wide variety of tissues. PRMT5 also associates specifically with the transcription start site region of the cyclin E1 promoter, and, therefore, is involved in the control of transcription and proliferation. The gene encoding human PRMT5 maps to chromosome 14q11.
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基因ID
- 10419
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UniProt
- O14744
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
抗原
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