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Periostin 抗体

POSTN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 2F7 unconjugated
产品编号 ABIN6944485
发货至: 中国
  • 抗原 See all Periostin (POSTN) 抗体
    Periostin (POSTN)
    适用
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    宿主
    • 81
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    克隆类型
    • 73
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    单克隆
    标记
    • 68
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    This Periostin antibody is un-conjugated
    应用范围
    • 77
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    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Human Perilipin-1 aa 400 to the C-terminus
    克隆位点
    2F7
    亚型
    IgG
    Top Product
    Discover our top product POSTN Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Periostin (POSTN)
    别名
    Periostin (POSTN 产品)
    背景

    Synonyms: Periostin, Osteoblast-specific factor 2, PN, OSF-2, POSTN, OSF2, PDLPOSTN.

    Background: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta and alpha(V)beta integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor _ 1(TGF _ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

    基因ID
    10631
    UniProt
    Q15063
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