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PARP1 抗体 (AA 150-250)

This anti-PARP1 antibody is a 兔 单克隆 antibody detecting PARP1 in WB, FACS 和 IF (cc). Suitable for 人.
产品编号 ABIN6944421
发货至: 中国

Quick Overview for PARP1 抗体 (AA 150-250) (ABIN6944421)

抗原

See all PARP1 抗体
PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

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宿主

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克隆类型

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单克隆

标记

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This PARP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

2A10
  • 抗原表位

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    AA 150-250

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide within Human PARP1 aa 150-250

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

    别名

    PARP

    背景

    Synonyms: Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1, PARP-1, ARTD1, ADPRT 1, PARP1

    Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].

    基因ID

    142

    UniProt

    P09874

    途径

    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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