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NDEL1 抗体 (N-Term)

The 兔 单克隆 anti-NDEL1 antibody (Clone 7A1) (ABIN6944228) specifically detects NDEL1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN6944228
发货至: 中国
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Quick Overview for NDEL1 抗体 (N-Term) (ABIN6944228)

抗原

See all NDEL1 抗体
NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

适用

  • 118
  • 34
  • 29
  • 2
  • 1

宿主

  • 112
  • 5
  • 1

克隆类型

  • 94
  • 24
单克隆

标记

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  • 1
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This NDEL1 antibody is un-conjugated

应用范围

  • 64
  • 52
  • 52
  • 18
  • 15
  • 14
  • 14
  • 12
  • 5
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

7A1
  • 抗原表位

    • 22
    • 15
    • 15
    • 15
    • 13
    • 3
    • 2
    • 2
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    • 1
    • 1
    • 1
    N-Term

    原理

    NDEL1 (7A1) Monoclonal Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein corresponding to the N-terminus of human Nudel.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IHC-P(1:200-400)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

    别名

    NDEL1

    背景

    Synonyms: Nuclear distribution protein nudE-like 1, Mitosin-associated protein 1, Protein Nudel, NDEL1, EOPA, MITAP1, NUDEL, nudE neurodevelopment protein 1 like 1, NDE1L1

    Background: Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

    基因ID

    81565

    UniProt

    Q9GZM8

    途径

    Regulation of Cell Size
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